Volume 4: Issue 2 - Winter 2008

Health

one less?

hpv vaccine may cause more harm than good

photo by katie stevens

by melissas schaaf

It may have saved her life. Laura Neal has never considered herself an at-risk individual when it comes to cancer, and maybe now she’ll never need to. Armed with a cervical cancer vaccine, she is one of many females who are battling against becoming one more statistic.

Encouraged by her nurse, the 20-year-old junior health and exercise science major received Gardasil, a vaccine designed for women as a prevention against the human papillomavirus. If contracted, HPV could potentially lead to cervical cancer. The vaccine was approved by the Food and Drug Administration in 2006 and made available to women nationwide. According to Merck & Co., the producers of Gardasil, almost 16 million females in the United States, have received at least one of the three required shots for Gardasil, including Neal. Yet, as Gardasil is a newer vaccine, the unknown side effects may cause more harm than good.

Since its approval, there have been over 9,000 reports submitted to the Vaccine Adverse Event Reporting System concerning associated side effects, approximately 6 percent of which express serious cases, including paralysis, Guillain-Barre Syndrome, chronic pain, neurological disorders and even death. According to the National Institute of Neurological Disorders and Stroke Web site, GBS is a rare disorder in which the body’s immune system attacks part of the peripheral nervous system, causing weakness in the muscles, potentially leading to paralysis.

Despite the considerable amount of adverse effects reported, for Neal the vaccine caused nothing more than some discomfort in her right arm where she received the injection.

“The shot hurt like a b****,” she said. “My arm was very sore for the next couple days and it really hurt to move or raise it.”

Neal noted that her nurse gave a consultation beforehand, stating that other women had complained about pain from receiving the shot as well. She received her second shot in January 2008, but said that it was not as painful as the first.

Even with the number of adverse side effect accounts, there have only been two or three reports of individuals fainting after receiving the vaccine at Hartshorn Health Services, according to immunization coordinator Lisa Duggan. Further, the number of Gardasil shots administered at Hartshorn has nearly doubled in the past two school years: 706 vaccinations were given to 443 individuals in 2007 to 2008, increased from 418 vaccinations distributed to 238 individuals in 2006 to 2007.

“I’m impressed with how many people have decided to get the vaccine,” Duggan said. “We’ve had very limited problems with it; only a handful of women have complained of a sore arm (after receiving it). But I have heard that it hurts more than other shots.” Gardasil has been advertised on television with a campaign that challenges women to be “One Less” statistic for cervical cancer. It is also promoted among several medical organizations, such as the Center for Disease Control and Prevention. Although the vaccine is highly recommended, it is not required, allowing individuals a personal decision as to whether or not they receive it.

“I actually heard about (the vaccine) from one of my friends and did a speech about HPV for one of my classes,” Neal said. “I figured that it would be a good decision to get it.”

Even though the vaccine is deemed safe and effective by both the CDC and the FDA, some individuals still have reservations about receiving the shot because of its infancy, as well as the unknown, long-term side effects. Neal’s roommate, 21-year-old Kirsten Stople, also a junior health and exercise science major, is one of those apprehensive individuals.

“(The vaccine) is so new. I almost feel like we’re lab rats,” Stople said. “I know they say it’s safe and effective, but you can never know for sure.”

According to a handout for the HPV vaccine, the most reported side-effects include pain, mild to moderate fever, and redness, swelling and itching at the injection site. Another common effect is syncope, or fainting.

According to Duggan, this is caused by a vaso-vagal reaction. In this reaction, the nervous reflexes that control heart rate and blood pressure behave abnormally causing a drop in blood pressure and a fainting spell, according to the Columbia University Medical Center Web site.

“This reaction is much more common in teens when they receive a shot, especially in women,” Duggan said. “So, when you have a vaccine aimed at teenage women, there are going to be higher rates of fainting.”

Personal testimonials of more serious disorders are reported to start surfacing five to 14 days after receiving a shot, whether it be the first, second or third. According to VAERS, the rare conditions reported after receiving Gardasil cannot be directly related to the vaccine. Many other factors could have caused them to surface. For some, though, it is enough that the conditions are possible at all to deter them from getting the vaccine.

“It kind of freaks me out,” Stople said. “With any vaccination there are possible risks. This one might prevent cervical cancer, but I don’t know if it’s going to affect other parts of my body.”

Another reason individuals may not be getting the vaccine is due to cost. Gardasil is a series of three shots: the second dose is given two months after dose one, and the third dose is given six months after dose two. Walgreen’s offers the vaccine for $176.99 per dose, costing $530.97 for the set of three. Hartshorn, however, distributes it for $140 per which comes to $420 for the trio. According to Duggan, Gardasil is frequently covered by health insurance and individuals are encouraged to check with their provider before they get it.

“Most services (at Hartshorn) are fee-based,” she said. “So when something isn’t covered, we try to provide it at a very reasonable price for students.”

Despite an increase in individuals receiving the vaccine on campus since its licensing, Duggan predicts that the number of vaccinations distributed will slow down, or even decrease in the future.

“I think we could be busy again this year and possibly next, but the CDC is really pushing that HPV vaccinations should be considered at a younger age and discussed by health care providers at appointments with 12 to 15-year-old girls,” she said. “As this becomes the norm, I think that we will see more and more women who have already had the vaccine before they come to college, and our numbers will start to drop off in the future.”

As Neal waits to get her final vaccination of the trio, she continues to advocate for it and support what Gardasil is created to do.

“I’d definitely say that it’s a good idea to get the shot because it’s an effective prevention method,” she said. “I’d say that the pros definitely outweigh the risks.”

Kira Kalush, sophomore international studies major, agrees.

“I would definitely suggest for other women to get the shots,” she said. “The whole idea of getting cervical cancer is more frightening than the unknown side effects. If there’s a way to avoid it, I’m going to try to.” Stople, however, is content to wait to make sure that Gardasil proves to be 100 percent safe.

“Part of me questions if I really need it right now,” she said. “I’d rather wait it out a little longer just to be safe. I’m not in a hurry.”



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